Highlights and News

Why Rheumatoid Arthritis Remission Rates Remain Stagnant - EMJ
Why Rheumatoid Arthritis Remission Rates Remain Stagnant  EMJ
The breakthrough that could stop arthritis and diabetes in their tracks - The i Paper
The breakthrough that could stop arthritis and diabetes in their tracks  The i Paper
New gene study offers arthritis treatment insights - HealthandCare.scot
New gene study offers arthritis treatment insights  HealthandCare.scot
PsA Takes Longer to Diagnose and Gets Less Early Therapy Than RA - HealthCentral
PsA Takes Longer to Diagnose and Gets Less Early Therapy Than RA  HealthCentral
Deep molecular profiling of synovial biopsies in the STRAP trial identifies signatures predictive of treatment response to biologic therapies in rheumatoid arthritis - Nature
Deep molecular profiling of synovial biopsies in the STRAP trial identifies signatures predictive of treatment response to biologic therapies in rheumatoid arthritis  Nature
Nurse-led care for people with early rheumatoid arthritis: Interview study with thematic analysis - Wiley Online Library
Nurse-led care for people with early rheumatoid arthritis: Interview study with thematic analysis  Wiley Online Library
Refractory Inflammatory Arthritis definition and model generated through patient and multi-disciplinary professional modified Delphi process - medRxiv
Refractory Inflammatory Arthritis definition and model generated through patient and multi-disciplinary professional modified Delphi process  medRxiv
Championing physio for inflammatory arthritis - The Chartered Society of Physiotherapy
Championing physio for inflammatory arthritis  The Chartered Society of Physiotherapy
Foot and Ankle Care in Inflammatory Arthritis - Arthritis Foundation
Foot and Ankle Care in Inflammatory Arthritis  Arthritis Foundation
Scientists discover natural ‘brake' that could stop harmful inflammation | UCL News - UCL - UCL | University College London
Scientists discover natural ‘brake' that could stop harmful inflammation | UCL News - UCL  UCL | University College London
Rheumatoid arthritis - The Lancet
Rheumatoid arthritis  The Lancet
Sustained Remission with Etanercept Tapering in Early Rheumatoid Arthritis - NEJM
Sustained Remission with Etanercept Tapering in Early Rheumatoid Arthritis  NEJM
RA-MAP, molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients - Nature
RA-MAP, molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients  Nature
Investigating the Impact of Sex on Outcomes in Juvenile Idiopathic Arthritis - medRxiv
Investigating the Impact of Sex on Outcomes in Juvenile Idiopathic Arthritis  medRxiv
Rheumatoid Arthritis Life Expectancy: What You Need to Know - HealthCentral
Rheumatoid Arthritis Life Expectancy: What You Need to Know  HealthCentral
Editor's Pick: JAK Inhibitors in the Treatment Algorithm of Rheumatoid Arthritis: A Review - EMJ
Editor's Pick: JAK Inhibitors in the Treatment Algorithm of Rheumatoid Arthritis: A Review  EMJ
Association between obesity and remission in rheumatoid arthritis patients treated with disease-modifying anti-rheumatic drugs - Nature
Association between obesity and remission in rheumatoid arthritis patients treated with disease-modifying anti-rheumatic drugs  Nature
Tofacitinib versus Methotrexate in Rheumatoid Arthritis - NEJM
Tofacitinib versus Methotrexate in Rheumatoid Arthritis  NEJM
Novel biomarkers of a peripheral blood interferon signature associated with drug-naïve early arthritis patients distinguish persistent from self-limiting disease course - Nature
Novel biomarkers of a peripheral blood interferon signature associated with drug-naïve early arthritis patients distinguish persistent from self-limiting disease course  Nature
Blocking the immune system in rheumatoid arthritis - The Pharmaceutical Journal
Blocking the immune system in rheumatoid arthritis  The Pharmaceutical Journal
Single-cell insights into immune dysregulation in rheumatoid arthritis flare versus drug-free remission - Nature
Single-cell insights into immune dysregulation in rheumatoid arthritis flare versus drug-free remission  Nature
Efficacy of B-Cell-Targeted Therapy with Rituximab in Patients with Rheumatoid Arthritis - NEJM
Efficacy of B-Cell-Targeted Therapy with Rituximab in Patients with Rheumatoid Arthritis  NEJM
Baricitinib versus Placebo or Adalimumab in Rheumatoid Arthritis - NEJM
Baricitinib versus Placebo or Adalimumab in Rheumatoid Arthritis  NEJM
Asian and older rheumatoid arthritis sufferers 50% less likely to receive targeted treatment, finds study - Medical Xpress
Asian and older rheumatoid arthritis sufferers 50% less likely to receive targeted treatment, finds study  Medical Xpress
Prediction of response of methotrexate in patients with rheumatoid arthritis using serum lipidomics | Scientific Reports - Nature
Prediction of response of methotrexate in patients with rheumatoid arthritis using serum lipidomics | Scientific Reports  Nature
Artificial intelligence in rheumatoid arthritis research: A bibliometric analysis from 2004 to 2023 - Wiley Online Library
Artificial intelligence in rheumatoid arthritis research: A bibliometric analysis from 2004 to 2023  Wiley Online Library
Treatment of Rheumatoid Arthritis by Selective Inhibition of T-Cell Activation with Fusion Protein CTLA4Ig - NEJM
Treatment of Rheumatoid Arthritis by Selective Inhibition of T-Cell Activation with Fusion Protein CTLA4Ig  NEJM
Therapies for Active Rheumatoid Arthritis after Methotrexate Failure - NEJM
Therapies for Active Rheumatoid Arthritis after Methotrexate Failure  NEJM
Meera Alagarajah on dealing with rheumatoid arthritis - Dentistry Online - Dentistry.co.uk
Meera Alagarajah on dealing with rheumatoid arthritis - Dentistry Online  Dentistry.co.uk
Difficult-to-Treat Rheumatoid Arthritis: Is Prevention Feasible? - MedPage Today
Difficult-to-Treat Rheumatoid Arthritis: Is Prevention Feasible?  MedPage Today
New 'highly effective' treatment for rheumatoid arthritis on the way after breakthrough - The i Paper
New 'highly effective' treatment for rheumatoid arthritis on the way after breakthrough  The i Paper
Early Treatment Boosts Long-term Rheumatoid Arthritis Outcomes - Medscape
Early Treatment Boosts Long-term Rheumatoid Arthritis Outcomes  Medscape
PEPITEM 'replacement therapy' shows potential for early-stage inflammatory arthritis - Medical Xpress
PEPITEM 'replacement therapy' shows potential for early-stage inflammatory arthritis  Medical Xpress
Treating rheumatoid arthritis with JAK inhibitors: What to know - Medical News Today
Treating rheumatoid arthritis with JAK inhibitors: What to know  Medical News Today
Rheumatoid arthritis and baking soda: The potential benefits - Medical News Today
Rheumatoid arthritis and baking soda: The potential benefits  Medical News Today
New drug Bimzelx shows promise as a treatment for psoriatic arthritis - Medical News Today
New drug Bimzelx shows promise as a treatment for psoriatic arthritis  Medical News Today
What Happens at the First Appointment With a Rheumatologist? - Everyday Health
What Happens at the First Appointment With a Rheumatologist?  Everyday Health
Ibuprofen for arthritis: Is it safe to take every day? - Medical News Today
Ibuprofen for arthritis: Is it safe to take every day?  Medical News Today
Weather, seasons, and rheumatoid arthritis flares - Medical News Today
Weather, seasons, and rheumatoid arthritis flares  Medical News Today
Integrating point-of-care ultrasound into rheumatology practice - Medycyna Praktyczna
Integrating point-of-care ultrasound into rheumatology practice  Medycyna Praktyczna
Turmeric for rheumatoid arthritis: Does it work? - Medical News Today
Turmeric for rheumatoid arthritis: Does it work?  Medical News Today
A New Study Sheds Light on the Early Roots of RA - HealthCentral
A New Study Sheds Light on the Early Roots of RA  HealthCentral
Rheumatoid arthritis: Could a test tell which biologic may be best? - Medical News Today
Rheumatoid arthritis: Could a test tell which biologic may be best?  Medical News Today
Pharmaceutical care in rheumatoid arthritis - Hospital Pharmacy Europe
Pharmaceutical care in rheumatoid arthritis  Hospital Pharmacy Europe
Rheumatoid Arthritis: Common Questions About Diagnosis and Management - American Academy of Family Physicians | AAFP
Rheumatoid Arthritis: Common Questions About Diagnosis and Management  American Academy of Family Physicians | AAFP
Treatments for rheumatoid arthritis: Traditional DMARDS vs. biologics - Medical News Today
Treatments for rheumatoid arthritis: Traditional DMARDS vs. biologics  Medical News Today
What to know about rheumatoid arthritis and intermittent fasting - Medical News Today
What to know about rheumatoid arthritis and intermittent fasting  Medical News Today
Rheumatoid Arthritis On The Rise Worldwide, AI-Powered Study Estimates - U.S. News & World Report
Rheumatoid Arthritis On The Rise Worldwide, AI-Powered Study Estimates  U.S. News & World Report
Minocycline for rheumatoid arthritis: What to know - Medical News Today
Minocycline for rheumatoid arthritis: What to know  Medical News Today
U.K. approves anti-inflammatory drugs to treat sickest covid-19 patients after strong results in clinical trial - The Washington Post
U.K. approves anti-inflammatory drugs to treat sickest covid-19 patients after strong results in clinical trial  The Washington Post
CAR T-cell therapy may be a ‘miracle,' but it is too soon to say ‘cure' - Healio
CAR T-cell therapy may be a ‘miracle,' but it is too soon to say ‘cure'  Healio
Infliximab and Methotrexate in the Treatment of Rheumatoid Arthritis - NEJM
Infliximab and Methotrexate in the Treatment of Rheumatoid Arthritis  NEJM
The Effect of Glucocorticoids on Joint Destruction in Rheumatoid Arthritis - NEJM
The Effect of Glucocorticoids on Joint Destruction in Rheumatoid Arthritis  NEJM
Ankylosing spondylitis: an update - Royal Australian College of General Practitioners (RACGP)
Ankylosing spondylitis: an update  Royal Australian College of General Practitioners (RACGP)
Chinese herbal remedy 'just as effective as methotrexate against arthritis' - Medical News Today
Chinese herbal remedy 'just as effective as methotrexate against arthritis'  Medical News Today
England | London | Six taken ill after drug trials - BBC
England | London | Six taken ill after drug trials  BBC
Blood test could provide an early arthritis warning - Nursing Times
Blood test could provide an early arthritis warning  Nursing Times
Rheumatoid arthritis: How to spot arthritis bumps - location and size - Daily Express
Rheumatoid arthritis: How to spot arthritis bumps - location and size  Daily Express
From sensitive scalp to voice changes - the hidden warnings arthritis is nearing - The Sun
From sensitive scalp to voice changes - the hidden warnings arthritis is nearing  The Sun
Mum who can't lean down to pick up baby warns: Catch arthritis early to save your joints - Daily Express
Mum who can't lean down to pick up baby warns: Catch arthritis early to save your joints  Daily Express

Articles/peer reviewed publications and
Lay Summaries

  • B cell synovitis and clinical phenotypes in rheumatoid arthritis: relationship to disease stages and drug exposure.
    Rivellese F, Humby F, Bugatti S, Fossati-Jimack L, Rizvi H, Lucchesi D, Lliso-Ribera G, Nerviani A, Hands RE, Giorli G, Frias B, Thorborn G, Jaworska E, John C, Goldmann K, Lewis MJ, Manzo A, Bombardieri M, Pitzalis C; PEAC- R4RA investigators. 
    Arthritis Rheumatol. 2019 Nov 29.
    https://doi.org/10.1002/art.41184
    See Lay Summary




The R4-RA trial is funded by the MRC-NIHR Efficacy and
Mechanism Evaluation Programme