Highlights and News

UK leads the world in rapid activation of complex early-phase ATiMP trial - NIHR
UK leads the world in rapid activation of complex early-phase ATiMP trial  NIHR
Rheumatoid arthritis patient trial backs up vaccination advantages of methotrexate delay - thepharmacist.co.uk
Rheumatoid arthritis patient trial backs up vaccination advantages of methotrexate delay  thepharmacist.co.uk
Why Rheumatoid Arthritis Remission Rates Remain Stagnant - EMJ
Why Rheumatoid Arthritis Remission Rates Remain Stagnant  EMJ
The breakthrough that could stop arthritis and diabetes in their tracks - The i Paper
The breakthrough that could stop arthritis and diabetes in their tracks  The i Paper
New gene study offers arthritis treatment insights - HealthandCare.scot
New gene study offers arthritis treatment insights  HealthandCare.scot
Nurse-led care for people with early rheumatoid arthritis: Interview study with thematic analysis - Wiley Online Library
Nurse-led care for people with early rheumatoid arthritis: Interview study with thematic analysis  Wiley Online Library
RA-MAP, molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients - Nature
RA-MAP, molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients  Nature
Championing physio for inflammatory arthritis - The Chartered Society of Physiotherapy
Championing physio for inflammatory arthritis  The Chartered Society of Physiotherapy
PsA Takes Longer to Diagnose and Gets Less Early Therapy Than RA - HealthCentral
PsA Takes Longer to Diagnose and Gets Less Early Therapy Than RA  HealthCentral
Rheumatoid arthritis - The Lancet
Rheumatoid arthritis  The Lancet
First UK patient treated in ‘OSCAR' COVID-19 research study, trialling experimental arthritis drug as treatment for coronavirus - Manchester University NHS Foundation Trust
First UK patient treated in ‘OSCAR' COVID-19 research study, trialling experimental arthritis drug as treatment for coronavirus  Manchester University NHS Foundation Trust
Foot and Ankle Care in Inflammatory Arthritis - Arthritis Foundation
Foot and Ankle Care in Inflammatory Arthritis  Arthritis Foundation
Crying out for equity: outcomes of rheumatic diseases confounded by ethnicity | Clinical Rheumatology - Springer Nature Link
Crying out for equity: outcomes of rheumatic diseases confounded by ethnicity | Clinical Rheumatology  Springer Nature Link
Sustained Remission with Etanercept Tapering in Early Rheumatoid Arthritis - The New England Journal of Medicine
Sustained Remission with Etanercept Tapering in Early Rheumatoid Arthritis  The New England Journal of Medicine
Tight Control of Psoriatic Arthritis: Real-World Outcomes From TICOPA - Rheumatology Advisor
Tight Control of Psoriatic Arthritis: Real-World Outcomes From TICOPA  Rheumatology Advisor
Blocking the immune system in rheumatoid arthritis - The Pharmaceutical Journal
Blocking the immune system in rheumatoid arthritis  The Pharmaceutical Journal
Breakthrough cell therapy could replace organ transplants - and save NHS millions - The i Paper
Breakthrough cell therapy could replace organ transplants - and save NHS millions  The i Paper
Deep molecular profiling of synovial biopsies in the STRAP trial identifies signatures predictive of treatment response to biologic therapies in rheumatoid arthritis - Nature
Deep molecular profiling of synovial biopsies in the STRAP trial identifies signatures predictive of treatment response to biologic therapies in rheumatoid arthritis  Nature
Editor's Pick: JAK Inhibitors in the Treatment Algorithm of Rheumatoid Arthritis: A Review - EMJ
Editor's Pick: JAK Inhibitors in the Treatment Algorithm of Rheumatoid Arthritis: A Review  EMJ
Tofacitinib versus Methotrexate in Rheumatoid Arthritis - The New England Journal of Medicine
Tofacitinib versus Methotrexate in Rheumatoid Arthritis  The New England Journal of Medicine
Artificial intelligence in rheumatoid arthritis research: A bibliometric analysis from 2004 to 2023 - Wiley Online Library
Artificial intelligence in rheumatoid arthritis research: A bibliometric analysis from 2004 to 2023  Wiley Online Library
Single-cell insights into immune dysregulation in rheumatoid arthritis flare versus drug-free remission - Nature
Single-cell insights into immune dysregulation in rheumatoid arthritis flare versus drug-free remission  Nature
Novel biomarkers of a peripheral blood interferon signature associated with drug-naïve early arthritis patients distinguish persistent from self-limiting disease course - Nature
Novel biomarkers of a peripheral blood interferon signature associated with drug-naïve early arthritis patients distinguish persistent from self-limiting disease course  Nature
Baricitinib versus Placebo or Adalimumab in Rheumatoid Arthritis - The New England Journal of Medicine
Baricitinib versus Placebo or Adalimumab in Rheumatoid Arthritis  The New England Journal of Medicine
Prediction of response of methotrexate in patients with rheumatoid arthritis using serum lipidomics | Scientific Reports - Nature
Prediction of response of methotrexate in patients with rheumatoid arthritis using serum lipidomics | Scientific Reports  Nature
Axl and MerTK regulate synovial inflammation and are modulated by IL-6 inhibition in rheumatoid arthritis - Nature
Axl and MerTK regulate synovial inflammation and are modulated by IL-6 inhibition in rheumatoid arthritis  Nature
Quell launches chill phase 1/2 trial for novel cartreg therapy - PharmaTimes
Quell launches chill phase 1/2 trial for novel cartreg therapy  PharmaTimes
Analysis of early changes in DNA methylation in synovial fibroblasts of RA patients before diagnosis - Nature
Analysis of early changes in DNA methylation in synovial fibroblasts of RA patients before diagnosis  Nature
Therapies for Active Rheumatoid Arthritis after Methotrexate Failure - The New England Journal of Medicine
Therapies for Active Rheumatoid Arthritis after Methotrexate Failure  The New England Journal of Medicine
Meera Alagarajah on dealing with rheumatoid arthritis - Dentistry Online - Dentistry.co.uk
Meera Alagarajah on dealing with rheumatoid arthritis - Dentistry Online  Dentistry.co.uk
Rheumatoid arthritis - Nature
Rheumatoid arthritis  Nature
PEPITEM 'replacement therapy' shows potential for early-stage inflammatory arthritis - Medical Xpress
PEPITEM 'replacement therapy' shows potential for early-stage inflammatory arthritis  Medical Xpress
Rheumatoid Arthritis: GLP-1 Drugs Like Ozempic May Decrease Flare-Ups - Healthline
Rheumatoid Arthritis: GLP-1 Drugs Like Ozempic May Decrease Flare-Ups  Healthline
Rheumatoid arthritis and baking soda: The potential benefits - Medical News Today
Rheumatoid arthritis and baking soda: The potential benefits  Medical News Today
Early intensive treatment of rheumatoid arthritis offers an opportunity to manage fatigue - News-Medical
Early intensive treatment of rheumatoid arthritis offers an opportunity to manage fatigue  News-Medical
Ibuprofen for arthritis: Is it safe to take every day? - Medical News Today
Ibuprofen for arthritis: Is it safe to take every day?  Medical News Today
Rheumatoid arthritis cure: Is it possible? - Medical News Today
Rheumatoid arthritis cure: Is it possible?  Medical News Today
Treating rheumatoid arthritis with JAK inhibitors: What to know - Medical News Today
Treating rheumatoid arthritis with JAK inhibitors: What to know  Medical News Today
Turmeric for rheumatoid arthritis: Does it work? - Medical News Today
Turmeric for rheumatoid arthritis: Does it work?  Medical News Today
New drug Bimzelx shows promise as a treatment for psoriatic arthritis - Medical News Today
New drug Bimzelx shows promise as a treatment for psoriatic arthritis  Medical News Today
Integrating point-of-care ultrasound into rheumatology practice - Medycyna Praktyczna
Integrating point-of-care ultrasound into rheumatology practice  Medycyna Praktyczna
Rheumatoid arthritis: Could a test tell which biologic may be best? - Medical News Today
Rheumatoid arthritis: Could a test tell which biologic may be best?  Medical News Today
I treated my rheumatoid arthritis with homeopathy and herbs - it was a waste of money - The i Paper
I treated my rheumatoid arthritis with homeopathy and herbs - it was a waste of money  The i Paper
Minocycline for rheumatoid arthritis: What to know - Medical News Today
Minocycline for rheumatoid arthritis: What to know  Medical News Today
UK waiting times for RA and PsA patients: an interview with Dr Marwan Bukhari, Consultant Rheumatologist at the University Hospitals of Morecambe Bay NHS Foundation Trust - News-Medical
UK waiting times for RA and PsA patients: an interview with Dr Marwan Bukhari, Consultant Rheumatologist at the University Hospitals of Morecambe Bay NHS Foundation Trust  News-Medical
Rheumatoid Arthritis: Common Questions About Diagnosis and Management - American Academy Of Family Physicians | AAFP
Rheumatoid Arthritis: Common Questions About Diagnosis and Management  American Academy Of Family Physicians | AAFP
Weather, seasons, and rheumatoid arthritis flares - Medical News Today
Weather, seasons, and rheumatoid arthritis flares  Medical News Today
Treatments for rheumatoid arthritis: Traditional DMARDS vs. biologics - Medical News Today
Treatments for rheumatoid arthritis: Traditional DMARDS vs. biologics  Medical News Today
Hydroxychloroquine for rheumatoid arthritis: Uses and more - Medical News Today
Hydroxychloroquine for rheumatoid arthritis: Uses and more  Medical News Today
What to know about rheumatoid arthritis and intermittent fasting - Medical News Today
What to know about rheumatoid arthritis and intermittent fasting  Medical News Today
Diagnosis and Management of Rheumatoid Arthritis - American Academy Of Family Physicians | AAFP
Diagnosis and Management of Rheumatoid Arthritis  American Academy Of Family Physicians | AAFP
Blood test could provide an early arthritis warning - Nursing Times
Blood test could provide an early arthritis warning  Nursing Times
U.K. approves anti-inflammatory drugs to treat sickest covid-19 patients after strong results in clinical trial - The Washington Post
U.K. approves anti-inflammatory drugs to treat sickest covid-19 patients after strong results in clinical trial  The Washington Post
Infliximab and Methotrexate in the Treatment of Rheumatoid Arthritis - The New England Journal of Medicine
Infliximab and Methotrexate in the Treatment of Rheumatoid Arthritis  The New England Journal of Medicine
Advances in the Treatment of Early Rheumatoid Arthritis - American Academy Of Family Physicians | AAFP
Advances in the Treatment of Early Rheumatoid Arthritis  American Academy Of Family Physicians | AAFP
The Effect of Glucocorticoids on Joint Destruction in Rheumatoid Arthritis - The New England Journal of Medicine
The Effect of Glucocorticoids on Joint Destruction in Rheumatoid Arthritis  The New England Journal of Medicine
Ankylosing spondylitis: an update - Royal Australian College of General Practitioners (RACGP)
Ankylosing spondylitis: an update  Royal Australian College of General Practitioners (RACGP)
Chinese herbal remedy 'just as effective as methotrexate against arthritis' - Medical News Today
Chinese herbal remedy 'just as effective as methotrexate against arthritis'  Medical News Today
England | London | Six taken ill after drug trials - BBC
England | London | Six taken ill after drug trials  BBC
From sensitive scalp to voice changes - the hidden warnings arthritis is nearing - The Sun
From sensitive scalp to voice changes - the hidden warnings arthritis is nearing  The Sun

Articles/peer reviewed publications and
Lay Summaries

  • B cell synovitis and clinical phenotypes in rheumatoid arthritis: relationship to disease stages and drug exposure.
    Rivellese F, Humby F, Bugatti S, Fossati-Jimack L, Rizvi H, Lucchesi D, Lliso-Ribera G, Nerviani A, Hands RE, Giorli G, Frias B, Thorborn G, Jaworska E, John C, Goldmann K, Lewis MJ, Manzo A, Bombardieri M, Pitzalis C; PEAC- R4RA investigators. 
    Arthritis Rheumatol. 2019 Nov 29.
    https://doi.org/10.1002/art.41184
    See Lay Summary




The R4-RA trial is funded by the MRC-NIHR Efficacy and
Mechanism Evaluation Programme