Highlights and News

Why Rheumatoid Arthritis Remission Rates Remain Stagnant - European Medical Journal
Why Rheumatoid Arthritis Remission Rates Remain Stagnant  European Medical Journal
Abatacept could delay rheumatoid arthritis for high-risk patients - The Pharmaceutical Journal
Abatacept could delay rheumatoid arthritis for high-risk patients  The Pharmaceutical Journal
New gene study offers arthritis treatment insights - HealthandCare.scot
New gene study offers arthritis treatment insights  HealthandCare.scot
Interventions supporting people from Black, Asian and Minority Ethnic groups in the United Kingdom with musculoskeletal disorders: a scoping review - Frontiers
Interventions supporting people from Black, Asian and Minority Ethnic groups in the United Kingdom with musculoskeletal disorders: a scoping review  Frontiers
Rheumatoid arthritis: Pretreatment may delay onset by up to 4 years - Medical News Today
Rheumatoid arthritis: Pretreatment may delay onset by up to 4 years  Medical News Today
New research reveals shared genetic link between endometriosis and immune conditions - University of Oxford
New research reveals shared genetic link between endometriosis and immune conditions  University of Oxford
Referring early arthritis patients within 6 weeks versus 12 weeks after symptom onset: an observational cohort study - The Lancet
Referring early arthritis patients within 6 weeks versus 12 weeks after symptom onset: an observational cohort study  The Lancet
Nurse-led care for people with early rheumatoid arthritis: Interview study with thematic analysis - Wiley Online Library
Nurse-led care for people with early rheumatoid arthritis: Interview study with thematic analysis  Wiley Online Library
Links between arthritis therapy and heart disease improvements - University of Leeds
Links between arthritis therapy and heart disease improvements  University of Leeds
Arthritis drug effective in treating sickest COVID-19 patients - Imperial College London
Arthritis drug effective in treating sickest COVID-19 patients  Imperial College London
RA-MAP, molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients - Nature
RA-MAP, molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients  Nature
Understanding Methotrexate - Arthritis Foundation
Understanding Methotrexate  Arthritis Foundation
Sustained Remission with Etanercept Tapering in Early Rheumatoid Arthritis - NEJM
Sustained Remission with Etanercept Tapering in Early Rheumatoid Arthritis  NEJM
Abatacept in individuals at high risk of rheumatoid arthritis (APIPPRA): a randomised, double-blind, multicentre, parallel, placebo-controlled, phase 2b clinical trial - The Lancet
Abatacept in individuals at high risk of rheumatoid arthritis (APIPPRA): a randomised, double-blind, multicentre, parallel, placebo-controlled, phase 2b clinical trial  The Lancet
Rheumatoid arthritis: management - The Pharmaceutical Journal
Rheumatoid arthritis: management  The Pharmaceutical Journal
Is There a Missing Link in Rheumatoid Arthritis Management? - European Medical Journal
Is There a Missing Link in Rheumatoid Arthritis Management?  European Medical Journal
Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial - Nature
Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial  Nature
Foot and Ankle Care in Inflammatory Arthritis - Arthritis Foundation
Foot and Ankle Care in Inflammatory Arthritis  Arthritis Foundation
Editor's Pick: JAK Inhibitors in the Treatment Algorithm of Rheumatoid Arthritis: A Review - European Medical Journal
Editor's Pick: JAK Inhibitors in the Treatment Algorithm of Rheumatoid Arthritis: A Review  European Medical Journal
Rheumatoid arthritis - The Lancet
Rheumatoid arthritis  The Lancet
Molecular Medicine for arthritis - University of Southampton
Molecular Medicine for arthritis  University of Southampton
Asian and older rheumatoid arthritis sufferers 50% less likely to receive targeted treatment, finds study - Medical Xpress
Asian and older rheumatoid arthritis sufferers 50% less likely to receive targeted treatment, finds study  Medical Xpress
Transcriptomic profiling of programmed cell death 1 (PD-1) expressing T cells in early rheumatoid arthritis identifies a decreased CD4 + PD-1 + signature post-treatment - Nature
Transcriptomic profiling of programmed cell death 1 (PD-1) expressing T cells in early rheumatoid arthritis identifies a decreased CD4 + PD-1 + signature post-treatment  Nature
When to Go to the Hospital With Rheumatoid Arthritis Symptoms - HealthCentral
When to Go to the Hospital With Rheumatoid Arthritis Symptoms  HealthCentral
Rheumatoid arthritis - The Lancet
Rheumatoid arthritis  The Lancet
Palliative care - World Health Organization (WHO)
Palliative care  World Health Organization (WHO)
PsA Takes Longer to Diagnose and Gets Less Early Therapy Than RA - HealthCentral
PsA Takes Longer to Diagnose and Gets Less Early Therapy Than RA  HealthCentral
2023 Management Recommendations of Bangladesh Rheumatology Society on Pharmacological Treatment of Rheumatoid Arthritis With Synthetic and Biologic Disease-Modifying Drugs - Cureus
2023 Management Recommendations of Bangladesh Rheumatology Society on Pharmacological Treatment of Rheumatoid Arthritis With Synthetic and Biologic Disease-Modifying Drugs  Cureus
Association between obesity and remission in rheumatoid arthritis patients treated with disease-modifying anti-rheumatic drugs - Nature
Association between obesity and remission in rheumatoid arthritis patients treated with disease-modifying anti-rheumatic drugs  Nature
Novel biomarkers of a peripheral blood interferon signature associated with drug-naïve early arthritis patients distinguish persistent from self-limiting disease course - Nature
Novel biomarkers of a peripheral blood interferon signature associated with drug-naïve early arthritis patients distinguish persistent from self-limiting disease course  Nature
Single-cell insights into immune dysregulation in rheumatoid arthritis flare versus drug-free remission - Nature
Single-cell insights into immune dysregulation in rheumatoid arthritis flare versus drug-free remission  Nature
Prediction of response of methotrexate in patients with rheumatoid arthritis using serum lipidomics | Scientific Reports - Nature
Prediction of response of methotrexate in patients with rheumatoid arthritis using serum lipidomics | Scientific Reports  Nature
Rheumatoid arthritis and baking soda: The potential benefits - Medical News Today
Rheumatoid arthritis and baking soda: The potential benefits  Medical News Today
Rheumatoid arthritis - Nature
Rheumatoid arthritis  Nature
Exercises to improve function of the rheumatoid hand (SARAH): a randomised controlled trial - The Lancet
Exercises to improve function of the rheumatoid hand (SARAH): a randomised controlled trial  The Lancet
Biomarkers of early stage osteoarthritis, rheumatoid arthritis and musculoskeletal health - Nature
Biomarkers of early stage osteoarthritis, rheumatoid arthritis and musculoskeletal health  Nature
Gene-edited stem cells aim to reverse rheumatoid arthritis - Drug Discovery News
Gene-edited stem cells aim to reverse rheumatoid arthritis  Drug Discovery News
Activation of Th lymphocytes alters pattern expression and cellular location of VIP receptors in healthy donors and early arthritis patients | Scientific Reports - Nature
Activation of Th lymphocytes alters pattern expression and cellular location of VIP receptors in healthy donors and early arthritis patients | Scientific Reports  Nature
Rheumatoid arthritis: Do gut bacteria play a role? - Medical News Today
Rheumatoid arthritis: Do gut bacteria play a role?  Medical News Today
Professor Appointed to Key Role to Improve Treatment for Rheumatic Conditions | Newswise - Newswise
Professor Appointed to Key Role to Improve Treatment for Rheumatic Conditions | Newswise  Newswise
Rheumatoid Arthritis Life Expectancy: What You Need to Know - HealthCentral
Rheumatoid Arthritis Life Expectancy: What You Need to Know  HealthCentral
Psoriatic arthritis: New drug Bimzelx shows promise as treatment - Medical News Today
Psoriatic arthritis: New drug Bimzelx shows promise as treatment  Medical News Today
Treating rheumatoid arthritis with JAK inhibitors: What to know - Medical News Today
Treating rheumatoid arthritis with JAK inhibitors: What to know  Medical News Today
Early Treatment Boosts Long-term Rheumatoid Arthritis Outcomes - Medscape
Early Treatment Boosts Long-term Rheumatoid Arthritis Outcomes  Medscape
UK waiting times for RA and PsA patients: an interview with Dr Marwan Bukhari, Consultant Rheumatologist at the University Hospitals of Morecambe Bay NHS Foundation Trust - News-Medical
UK waiting times for RA and PsA patients: an interview with Dr Marwan Bukhari, Consultant Rheumatologist at the University Hospitals of Morecambe Bay NHS Foundation Trust  News-Medical
Turmeric for rheumatoid arthritis: Does it work? - Medical News Today
Turmeric for rheumatoid arthritis: Does it work?  Medical News Today
Rheumatoid arthritis: Early menopause among factors for higher risk - Medical News Today
Rheumatoid arthritis: Early menopause among factors for higher risk  Medical News Today
What Happens at the First Appointment With a Rheumatologist? - Everyday Health
What Happens at the First Appointment With a Rheumatologist?  Everyday Health
New 'highly effective' treatment for rheumatoid arthritis on the way after breakthrough - The i Paper
New 'highly effective' treatment for rheumatoid arthritis on the way after breakthrough  The i Paper
Rheumatoid Arthritis Itching: Causes and Relief - HealthCentral
Rheumatoid Arthritis Itching: Causes and Relief  HealthCentral
22 natural treatments for psoriatic arthritis - Medical News Today
22 natural treatments for psoriatic arthritis  Medical News Today
Rheumatoid Arthritis in the Wrist: Symptoms, Treatments and More - HealthCentral
Rheumatoid Arthritis in the Wrist: Symptoms, Treatments and More  HealthCentral
Rheumatoid arthritis severity scale: How it works and outlook - Medical News Today
Rheumatoid arthritis severity scale: How it works and outlook  Medical News Today
Minocycline for rheumatoid arthritis: What to know - Medical News Today
Minocycline for rheumatoid arthritis: What to know  Medical News Today
Infliximab and Methotrexate in the Treatment of Rheumatoid Arthritis - NEJM
Infliximab and Methotrexate in the Treatment of Rheumatoid Arthritis  NEJM
Ankylosing spondylitis: an update - Royal Australian College of General Practitioners (RACGP)
Ankylosing spondylitis: an update  Royal Australian College of General Practitioners (RACGP)
The Effect of Glucocorticoids on Joint Destruction in Rheumatoid Arthritis - NEJM
The Effect of Glucocorticoids on Joint Destruction in Rheumatoid Arthritis  NEJM
Blood test could provide an early arthritis warning - Nursing Times
Blood test could provide an early arthritis warning  Nursing Times

Articles/peer reviewed publications and
Lay Summaries

  • B cell synovitis and clinical phenotypes in rheumatoid arthritis: relationship to disease stages and drug exposure.
    Rivellese F, Humby F, Bugatti S, Fossati-Jimack L, Rizvi H, Lucchesi D, Lliso-Ribera G, Nerviani A, Hands RE, Giorli G, Frias B, Thorborn G, Jaworska E, John C, Goldmann K, Lewis MJ, Manzo A, Bombardieri M, Pitzalis C; PEAC- R4RA investigators. 
    Arthritis Rheumatol. 2019 Nov 29.
    https://doi.org/10.1002/art.41184
    See Lay Summary




The R4-RA trial is funded by the MRC-NIHR Efficacy and
Mechanism Evaluation Programme